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The potential of mechanistic information organised within the AOP framework to increase regulatory uptake of the developmental neurotoxicity (DNT) in vitro battery of assays

A major challenge in regulatory developmental neurotoxicity (DNT) assessment is lack of toxicological information for many compounds. Therefore, the Test Guidelines programme of the Organisation for Economic Cooperation and Development (OECD) took the initiative to coordinate an international collab...

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Publicado en:Reprod Toxicol
Autores principales: Sachana, Magdalini, Willett, Catherine, Pistollato, Francesca, Bal-Price, Anna
Formato: Artigo
Lenguaje:Inglês
Publicado: Pergamon In Cooperation With The Reproductive Toxicology Center 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8279093/
https://ncbi.nlm.nih.gov/pubmed/34147625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reprotox.2021.06.006
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