Screening of Compounds for Anti-tuberculosis Activity, and in vitro and in vivo Evaluation of Potential Candidates

Tuberculosis (TB) is a debilitating infectious disease responsible for more than one million deaths per year. The emergence of drug-resistant TB poses an urgent need for the development of new anti-TB drugs. In this study, we screened a library of over 4,000 small molecules and found that orbifloxac...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Zhou, Wei, Yang, Bing, Zou, Yanyan, Rahman, Khaista, Cao, Xiaojian, Lei, Yingying, Lai, Ren, Fu, Zhen F., Chen, Xi, Cao, Gang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8278749/
https://ncbi.nlm.nih.gov/pubmed/34276592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2021.658637
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