PSA-targeted Alpha-, Beta- and Positron Emitting Immuno-Theranostics in Murine Prostate Cancer Models and Non-Human Primates

PURPOSE: Most prostate cancer (PCa) patients treated with androgen receptor (AR)-signaling inhibitors develop therapeutic resistance due to restoration of AR-functionality. Thus, there is a critical need for novel treatment approaches. Here we investigate the theranostic potential of hu5A10, a human...

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Vydáno v:Clin Cancer Res
Hlavní autoři: Veach, Darren R., Storey, Claire M., Lückerath, Katharina, Braun, Katharina, von Bodman, Christian, Lamminmäki, Urpo, Kalidindi, Teja, Strand, Sven-Erik, Strand, Joanna, Altai, Mohamed, Damoiseaux, Robert, Zanzonico, Pat, Benabdallah, Nadia, Pankov, Dmitry, Scher, Howard I., Scardino, Peter, Larson, Steven M., Lilja, Hans, McDevitt, Michael R., Thorek, Daniel L. J., Ulmert, David
Médium: Artigo
Jazyk:Inglês
Vydáno: 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8278668/
https://ncbi.nlm.nih.gov/pubmed/33441295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-20-3614
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