Efficiency and Toxicity of Ruxolitinib as a Salvage Treatment for Steroid-Refractory Chronic Graft-Versus-Host Disease

Graft-versus-host disease (GVHD), especially steroid-refractory GVHD, remains a life-threatening complication after hematopoietic stem cell transplantation (HSCT). The effect of the JAK1/2 kinase inhibitor ruxolitinib on treating steroid-refractory acute GVHD has been verified by the REACH1/2 study;...

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Udgivet i:Front Immunol
Main Authors: Wang, Dong, Liu, Yin, Lai, Xiaoxuan, Chen, Jia, Cheng, Qiao, Ma, Xiao, Lin, Zhihong, Wu, Depei, Xu, Yang
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8278571/
https://ncbi.nlm.nih.gov/pubmed/34276662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.673636
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