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Nargenicin A1 attenuates lipopolysaccharide-induced inflammatory and oxidative response by blocking the NF-κB signaling pathway

Inflammation caused by the excessive production of pro-inflammatory mediators and cytokines in abnormally activated macrophages promotes the initiation and progression of many diseases along with oxidative stress. Previous studies have suggested that nargenicin A1, an antibacterial macrolide isolate...

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Detalhes bibliográficos
Publicado no:EXCLI J
Main Authors: Kwon, Da Hye, Kim, Gi-Young, Cha, Hee-Jae, Kim, Suhkmann, Kim, Heui-Soo, Hwang, Hye-Jin, Choi, Yung Hyun
Formato: Artigo
Idioma:Inglês
Publicado em: Leibniz Research Centre for Working Environment and Human Factors 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8278209/
https://ncbi.nlm.nih.gov/pubmed/34267609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17179/excli2021-3506
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