PU.1 inhibition attenuates atrial fibrosis and atrial fibrillation vulnerability induced by angiotensin‐II by reducing TGF‐β1/Smads pathway activation

Fibrosis serves a critical role in driving atrial remodelling‐mediated atrial fibrillation (AF). Abnormal levels of the transcription factor PU.1, a key regulator of fibrosis, are associated with cardiac injury and dysfunction following acute viral myocarditis. However, the role of PU.1 in atrial fi...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Hu, Juan, Zhang, Jing‐Jing, Li, Li, Wang, Shan‐Ling, Yang, Hai‐Tao, Fan, Xian‐Wei, Zhang, Lei‐Ming, Hu, Guang‐Ling, Fu, Hai‐Xia, Song, Wei‐Feng, Yan, Li‐Jie, Liu, Jing‐Jing, Wu, Jin‐Tao, Kong, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8278085/
https://ncbi.nlm.nih.gov/pubmed/34132026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16678
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