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Sorafenib fails to trigger ferroptosis across a wide range of cancer cell lines

Sorafenib, a protein kinase inhibitor approved for the treatment of hepatocellular carcinoma and advanced renal cell carcinoma, has been repeatedly reported to induce ferroptosis by possibly involving inhibition of the cystine/glutamate antiporter, known as system x(c)(−). Using a combination of wel...

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Vydáno v:Cell Death Dis
Hlavní autoři: Zheng, Jiashuo, Sato, Mami, Mishima, Eikan, Sato, Hideyo, Proneth, Bettina, Conrad, Marcus
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8277867/
https://ncbi.nlm.nih.gov/pubmed/34257282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03998-w
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