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Sorafenib fails to trigger ferroptosis across a wide range of cancer cell lines
Sorafenib, a protein kinase inhibitor approved for the treatment of hepatocellular carcinoma and advanced renal cell carcinoma, has been repeatedly reported to induce ferroptosis by possibly involving inhibition of the cystine/glutamate antiporter, known as system x(c)(−). Using a combination of wel...
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| Veröffentlicht in: | Cell Death Dis |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8277867/ https://ncbi.nlm.nih.gov/pubmed/34257282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03998-w |
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