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IL-15 and PIM kinases direct the metabolic programming of intestinal intraepithelial lymphocytes
Intestinal intraepithelial lymphocytes (IEL) are an abundant population of tissue-resident T cells that protect and maintain the intestinal barrier. IEL respond to epithelial cell-derived IL-15, which is complexed to the IL-15 receptor α chain (IL-15/Rα). IL-15 is essential both for maintaining IEL...
Enregistré dans:
| Publié dans: | Nat Commun |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8277781/ https://ncbi.nlm.nih.gov/pubmed/34257288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24473-2 |
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