Relationships Between Highly Recurrent Tumor Suppressor Alterations in 489 Leiomyosarcomas

BACKGROUND: Leiomyosarcoma (LMS) is the most common soft tissue and uterine sarcoma, but no standard therapy is available for recurrent or metastatic LMS. TP53, p16/RB1, and PI3K/mTOR pathway dysregulations are recurrent events, and some LMS express estrogen receptor (ER) and/or progesterone recepto...

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Publicado en:Cancer
Autores principales: Schaefer, Inga-Marie, Lundberg, Meijun Z., Demicco, Elizabeth G., Przybyl, Joanna, Matusiak, Magdalena, Chibon, Frédéric, Ingram, Davis R., Hornick, Jason L., Wang, Wei-Lien, Bauer, Sebastian, Baker, Laurence H., Lazar, Alexander J., van de Rijn, Matt, Mariño-Enríquez, Adrian, Fletcher, Jonathan A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2021
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8277678/
https://ncbi.nlm.nih.gov/pubmed/33788262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.33542
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