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Designing multivalent immunogens for alphavirus vaccine optimization

There is a pressing need for vaccines against mosquito-borne alphaviruses such as Venezuelan and eastern equine encephalitis viruses (VEEV, EEEV). We demonstrate an approach to vaccine development based on physicochemical properties (PCP) of amino acids to design a PCP-consensus sequence of the epit...

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Bibliografische gegevens
Gepubliceerd in:Virology
Hoofdauteurs: Read, Christopher M., Plante, Kenneth, Rafael, Grace, Rossi, Shannan L., Braun, Werner, Weaver, Scott C., Schein, Catherine H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8277671/
https://ncbi.nlm.nih.gov/pubmed/33823988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2020.11.010
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