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A computational model of pig ventricular cardiomyocyte electrophysiology and calcium handling: Translation from pig to human electrophysiology

The pig is commonly used as an experimental model of human heart disease, including for the study of mechanisms of arrhythmia. However, there exist differences between human and porcine cellular electrophysiology: The pig action potential (AP) has a deeper phase-1 notch, a longer duration at 50% rep...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Gaur, Namit, Qi, Xiao-Yan, Benoist, David, Bernus, Olivier, Coronel, Ruben, Nattel, Stanley, Vigmond, Edward J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8277015/
https://ncbi.nlm.nih.gov/pubmed/34191797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1009137
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