Dual modes of CRISPR-associated transposon homing

Tn7-like transposons have co-opted CRISPR systems, including class 1 type I-F, I-B, and class 2 type V-K. Intriguingly, although these CRISPR-associated transposases (CASTs) undergo robust CRISPR RNA (crRNA)-guided transposition, they are almost never found in sites targeted by the crRNAs encoded by...

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Bibliographische Detailangaben
Veröffentlicht in:Cell
Hauptverfasser: Saito, Makoto, Ladha, Alim, Strecker, Jonathan, Faure, Guilhem, Neumann, Edwin, Altae-Tran, Han, Macrae, Rhiannon K., Zhang, Feng
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8276595/
https://ncbi.nlm.nih.gov/pubmed/33770501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2021.03.006
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