Combined Biosynthetic Pathway Engineering and Storage Pool Expansion for High-Level Production of Ergosterol in Industrial Saccharomyces cerevisiae

Ergosterol, a terpenoid compound produced by fungi, is an economically important metabolite serving as the direct precursor of steroid drugs. Herein, ergsosterol biosynthetic pathway modification combined with storage capacity enhancement was proposed to synergistically improve the production of erg...

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Dades bibliogràfiques
Publicat a:Front Bioeng Biotechnol
Autors principals: Sun, Zhi-Jiao, Lian, Jia-Zhang, Zhu, Li, Jiang, Yi-Qi, Li, Guo-Si, Xue, Hai-Long, Wu, Mian-Bin, Yang, Li-Rong, Lin, Jian-Ping
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Bioengineering and Biotechnology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8275991/
https://ncbi.nlm.nih.gov/pubmed/34268298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2021.681666
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