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Cell type-specific roles of PAR1 in Coxsackievirus B3 infection

Protease-activated receptor 1 (PAR1) is widely expressed in humans and mice, and is activated by a variety of proteases, including thrombin. Recently, we showed that PAR1 contributes to the innate immune response to viral infection. Mice with a global deficiency of PAR1 expressed lower levels of CXC...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bode, Michael F., Schmedes, Clare M., Egnatz, Grant J., Bharathi, Vanthana, Hisada, Yohei M., Martinez, David, Kawano, Tomohiro, Weithauser, Alice, Rosenfeldt, Leah, Rauch, Ursula, Palumbo, Joseph S., Antoniak, Silvio, Mackman, Nigel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8275627/
https://ncbi.nlm.nih.gov/pubmed/34253819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-93759-8
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