Versatile nonviral delivery system for multiplex gene-editing in the liver

Recent advances in CRISPR present attractive genome-editing toolsets to implement therapeutic strategies at the genetic level. Here, we report a liposome-coated mesoporous silica nanoparticle (lipoMSN) as an effective CRISPR delivery system for multiplex gene-editing in the liver. The use of MSN pro...

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Detalles Bibliográficos
Publicado en:Adv Mater
Main Authors: Gong, Jing, Wang, Hong-Xia, Lao, Yeh-Hsing, Hu, Hanze, Vatan, Naazanene, Guo, Jonathan, Ho, Tzu-Chieh, Huang, Dantong, Li, Mingqiang, Shao, Dan, Leong, Kam W.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8274731/
https://ncbi.nlm.nih.gov/pubmed/33053221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adma.202003537
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