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A Dynamic Energy Budget (DEB) based modeling framework to describe tumor-in-host growth inhibition and cachexia onset during anticancer treatment in in vivo xenograft studies

Cancer anorexia-cachexia syndrome (CACS) is a very severe complication of cancer for which an adequate therapeutic strategy has not yet been defined. Recently, a notable number of new animal models of human CACS has been made available for translational purposes. Under the assumption that tumor-indu...

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發表在:Oncotarget
Main Authors: Tosca, Elena Maria, Rocchetti, Maurizio, Magni, Paolo
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8274726/
https://ncbi.nlm.nih.gov/pubmed/34262653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27960
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