ILRUN Downregulates ACE2 Expression and Blocks Infection of Human Cells by SARS-CoV-2

The human protein-coding gene ILRUN (inflammation and lipid regulator with UBA-like and NBR1-like domains; previously C6orf106) was identified as a proviral factor for Hendra virus infection and was recently characterized to function as an inhibitor of type I interferon expression. Here, we have uti...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Tribolet, Leon, Alexander, Marina R., Brice, Aaron M., van Vuren, Petrus Jansen, Rootes, Christina L., Mara, Kostlend, McDonald, Meg, Bruce, Kerri L., Gough, Tamara J., Shi, Shuning, Cowled, Christopher, Bean, Andrew G. D., Stewart, Cameron R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Cellular Response to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8274604/
https://ncbi.nlm.nih.gov/pubmed/33963054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00327-21
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