Lopinavir-ritonavir and hydroxychloroquine for critically ill patients with COVID-19: REMAP-CAP randomized controlled trial

PURPOSE: To study the efficacy of lopinavir-ritonavir and hydroxychloroquine in critically ill patients with coronavirus disease 2019 (COVID-19). METHODS: Critically ill adults with COVID-19 were randomized to receive lopinavir-ritonavir, hydroxychloroquine, combination therapy of lopinavir-ritonavi...

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Detalhes bibliográficos
Publicado no:Intensive Care Med
Main Authors: Arabi, Yaseen M., Gordon, Anthony C., Derde, Lennie P. G., Nichol, Alistair D., Murthy, Srinivas, Beidh, Farah Al, Annane, Djillali, Swaidan, Lolowa Al, Beane, Abi, Beasley, Richard, Berry, Lindsay R., Bhimani, Zahra, Bonten, Marc J. M., Bradbury, Charlotte A., Brunkhorst, Frank M., Buxton, Meredith, Buzgau, Adrian, Cheng, Allen, De Jong, Menno, Detry, Michelle A., Duffy, Eamon J., Estcourt, Lise J., Fitzgerald, Mark, Fowler, Rob, Girard, Timothy D., Goligher, Ewan C., Goossens, Herman, Haniffa, Rashan, Higgins, Alisa M., Hills, Thomas E., Horvat, Christopher M., Huang, David T., King, Andrew J., Lamontagne, Francois, Lawler, Patrick R., Lewis, Roger, Linstrum, Kelsey, Litton, Edward, Lorenzi, Elizabeth, Malakouti, Salim, McAuley, Daniel F., McGlothlin, Anna, Mcguinness, Shay, McVerry, Bryan J., Montgomery, Stephanie K., Morpeth, Susan C., Mouncey, Paul R., Orr, Katrina, Parke, Rachael, Parker, Jane C., Patanwala, Asad E., Rowan, Kathryn M., Santos, Marlene S., Saunders, Christina T., Seymour, Christopher W., Shankar-Hari, Manu, Tong, Steven Y. C., Turgeon, Alexis F., Turner, Anne M., Van de Veerdonk, Frank Leo, Zarychanski, Ryan, Green, Cameron, Berry, Scott, Marshall, John C., McArthur, Colin, Angus, Derek C., Webb, Steven A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2021
Assuntos:
Original
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8274471/
https://ncbi.nlm.nih.gov/pubmed/34251506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00134-021-06448-5
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