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Super-Resolution Fluorescence Imaging Reveals That Serine Incorporator Protein 5 Inhibits Human Immunodeficiency Virus Fusion by Disrupting Envelope Glycoprotein Clusters

Serine incorporator protein 5 (SERINC5) is the host anti-retroviral factor that reduces HIV-1 infectivity by incorporating into virions and inhibiting the envelope glycoprotein (Env) mediated virus fusion with target cells. We and others have shown that SERINC5 incorporation into virions alters the...

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Detalhes bibliográficos
Publicado no:ACS Nano
Main Authors: Chen, Yen-Cheng, Sood, Chetan, Marin, Mariana, Aaron, Jesse, Gratton, Enrico, Salaita, Khalid, Melikyan, Gregory B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8274448/
https://ncbi.nlm.nih.gov/pubmed/32441921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.0c02699
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