Evaluation of switch-mediated costimulation in trans on universal CAR-T cells (UniCAR) targeting CD123-positive AML

Chimeric antigen receptor T cells (CAR-T) targeting CD19 have achieved significant success in patients with B cell malignancies. To date, implementation of CAR-T in other indications remains challenging due to the lack of truly tumor-specific antigens as well as control of CAR-T activity in patients...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Meyer, Jan-Erik, Loff, Simon, Dietrich, Josephine, Spehr, Johannes, Jurado Jiménez, Gabriel, von Bonin, Malte, Ehninger, Gerhard, Cartellieri, Marc, Ehninger, Armin
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2021
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8274446/
https://ncbi.nlm.nih.gov/pubmed/34290907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2021.1945804
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