Genomic identification of sarcoma radiosensitivity and the clinical implications for radiation dose personalization

BACKGROUND: Soft-tissue sarcomas (STS) are heterogeneous with variable response to radiation therapy (RT). Utilizing the radiosensitivity index (RSI) we estimated the radiobiologic ratio of lethal to sublethal damage (α/β), genomic-adjusted radiation dose(GARD), and in-turn a biological effective ra...

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Foilsithe in:Transl Oncol
Main Authors: Yang, George, Yuan, Zhigang, Ahmed, Kamran, Welsh, Eric A., Fulp, William J., Gonzalez, Ricardo J., Mullinax, John E., Letson, Douglas, Bui, Marilyn, Harrison, Louis B., Scott, Jacob G., Torres-Roca, Javier F., Naghavi, Arash O.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Neoplasia Press 2021
Ábhair:
Original Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8274330/
https://ncbi.nlm.nih.gov/pubmed/34246048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2021.101165
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