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Automated Intracellular Pharmacological Electrophysiology for Ligand-Gated Ionotropic Receptor and Pharmacology Screening

Communication between neuronal cells, which is central to brain function, is performed by several classes of ligand-gated ionotropic receptors. The gold-standard technique for measuring rapid receptor response to agonist is manual patch-clamp electrophysiology, capable of the highest temporal resolu...

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Detalles Bibliográficos
Publicado en:Mol Pharmacol
Main Authors: Perszyk, Riley E., Yip, Mighten C., McConnell, Ona L., Wang, Eric T., Jenkins, Andrew, Traynelis, Stephen F., Forest, Craig R.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8274318/
https://ncbi.nlm.nih.gov/pubmed/33958481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/molpharm.120.000195
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