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Thymic atrophy creates holes in Treg‐mediated immuno‐regulation via impairment of an antigen‐specific clone
Age‐related thymic atrophy results in reduced output of naïve conventional T (Tcon) cells. However, its impact on regulatory T (Treg) cells is insufficiently understood. Given evidence that thymic Treg (tTreg) cell generation is enhanced in the aged, atrophy thymus and that the aged periphery accumu...
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| Udgivet i: | Immunology |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8274191/ https://ncbi.nlm.nih.gov/pubmed/33786850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.13333 |
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