NLR family pyrin domain containing 3 (NLRP3) and caspase 1 (CASP1) modulation by intracellular Cl(–) concentration

The impairment of the cystic fibrosis transmembrane conductance regulator (CFTR) activity induces intracellular chloride (Cl(–)) accumulation. The anion Cl(–), acting as a second messenger, stimulates the secretion of interleukin‐1β (IL‐1β), which starts an autocrine positive feedback loop. Here, we...

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Xehetasun bibliografikoak
Argitaratua izan da:Immunology
Egile Nagusiak: Clauzure, Mariángeles, Valdivieso, Ángel G., Dugour, Andrea V., Mori, Consuelo, Massip‐Copiz, María M., Aguilar, María Á., Sotomayor, Verónica, Asensio, Cristian J. A., Figueroa, Juan M., Santa‐Coloma, Tomás A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2021
Gaiak:
Original Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8274155/
https://ncbi.nlm.nih.gov/pubmed/33835494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.13336
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