Colombian Scorpion Centruroides margaritatus: Purification and Characterization of a Gamma Potassium Toxin with Full-Block Activity on the hERG1 Channel

The Colombian scorpion Centruroides margaritatus produces a venom considered of low toxicity. Nevertheless, there are known cases of envenomation resulting in cardiovascular disorders, probably due to venom components that target ion channels. Among them, the human ether-à-go-go-Related gene (hERG1)...

Full description

Saved in:
Bibliographic Details
Published in:Toxins (Basel)
Main Authors: Beltrán-Vidal, José, Carcamo-Noriega, Edson, Pastor, Nina, Zamudio-Zuñiga, Fernando, Guerrero-Vargas, Jimmy Alexander, Castaño, Santiago, Possani, Lourival Domingos, Restano-Cassulini, Rita
Format: Artigo
Language:Inglês
Published: MDPI 2021
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8273696/
https://ncbi.nlm.nih.gov/pubmed/34201318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins13060407
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items