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Effect of midodrine versus placebo on time to vasopressor discontinuation in patients with persistent hypotension in the intensive care unit (MIDAS): an international randomised clinical trial

PURPOSE: ICU discharge is often delayed by a requirement for intravenous vasopressor medications to maintain normotension. We hypothesised that the administration of midodrine, an oral α(1)-adrenergic agonist, as adjunct to standard treatment shortens the duration of intravenous vasopressor requirem...

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Detalhes bibliográficos
Publicado no:Intensive Care Med
Main Authors: Santer, Peter, Anstey, Matthew H., Patrocínio, Maria D., Wibrow, Bradley, Teja, Bijan, Shay, Denys, Shaefi, Shahzad, Parsons, Charles S., Houle, Timothy T., Eikermann, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8273663/
https://ncbi.nlm.nih.gov/pubmed/32885276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00134-020-06216-x
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