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Pharmacogenomics of Impaired Tyrosine Kinase Inhibitor Response: Lessons Learned From Chronic Myelogenous Leukemia

The use of small molecules became one key cornerstone of targeted anti-cancer therapy. Among them, tyrosine kinase inhibitors (TKIs) are especially important, as they were the first molecules to proof the concept of targeted anti-cancer treatment. Since 2001, TKIs can be successfully used to treat c...

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Bibliographic Details
Published in:Front Pharmacol
Main Authors: Kaehler, Meike, Cascorbi, Ingolf
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8273252/
https://ncbi.nlm.nih.gov/pubmed/34262462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.696960
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