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Nanoparticles for co-delivery of Osimertinib and Selumetinib to Overcome Osimertinib-acquired Resistance in Non-small Cell Lung Cancer

Osimertinib (OSI) is the first FDA-approved third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI). It can be used for treating non-small cell lung cancer (NSCLC) patients with activating EGFR mutation and for patients who are resistant to first-generation EGFR TKIs...

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Bibliographic Details
Published in:Acta Biomater
Main Authors: Chen, Wu, Yu, Danlei, Sun, Shi-Yong, Li, Feng
Format: Artigo
Language:Inglês
Published: 2021
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8273131/
https://ncbi.nlm.nih.gov/pubmed/34048974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2021.05.018
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