Two patients with chronic mucocutaneous candidiasis caused by TRAF3IP2 deficiency

BACKGROUND: TRAF3IP2 (Act1) is an adapter protein that interacts with IL-17R via its SEF/IL-17R (SEFIR) domain and coordinates two separate pro-inflammatory pathways following IL-17 cytokine stimulation. OBJECTIVE: To elucidate the immunological consequences of TRAF3IP2 homozygous mutations to impro...

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Publicado en:J Allergy Clin Immunol
Main Authors: Shafer, Samantha, Yao, Yikun, Comrie, William, Cook, Sarah, Zhang, Yu, Yesil, Gözde, Karakoç-Aydiner, Elif, Baris, Safa, Cokugras, Haluk, Aydemir, Sezin, Kiykim, Ayca, Ozen, Ahmet, Lenardo, Michael
Formato: Artigo
Idioma:Inglês
Publicado: 2021
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8273085/
https://ncbi.nlm.nih.gov/pubmed/33359359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2020.12.629
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