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Retinal Protein O-GlcNAcylation and the Ocular Renin-Angiotensin System: Signaling Cross-Roads in Diabetic Retinopathy

It is well established that diabetes and its associated hyperglycemia negatively impact retinal function, yet we know little about the role played by augmented flux through the hexosamine biosynthetic pathway (HBP). This offshoot of the glycolytic pathway produces UDP-N-acetyl-glucosamine, which ser...

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Detalhes bibliográficos
Publicado no:Curr Diabetes Rev
Main Authors: Dierschke, Sadie K., Dennis, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2022
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8272735/
https://ncbi.nlm.nih.gov/pubmed/33430751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1573399817999210111205933
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