Genetic susceptibility to multiple sclerosis: interactions between conserved extended haplotypes of the MHC and other susceptibility regions

BACKGROUND: To study the accumulation of MS-risk resulting from different combinations of MS-associated conserved-extended-haplotypes (CEHs) of the MHC and three non-MHC “risk-haplotypes” nearby genes EOMES, ZFP36L1, and CLEC16A. Many haplotypes are MS-associated despite having population-frequencie...

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Vydáno v:BMC Med Genomics
Hlavní autoři: Goodin, D. S., Khankhanian, P., Gourraud, P. A., Vince, N.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8272333/
https://ncbi.nlm.nih.gov/pubmed/34246256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-021-01018-6
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