Sequence analysis of Plasmodium vivax Duffy binding proteins reveals the presence of unique haplotypes and diversifying selection in Ethiopian isolates

BACKGROUND: Red blood cell invasion by the Plasmodium vivax merozoite requires interaction between the Duffy antigen receptor for chemokines (DARC) and the P. vivax Duffy-binding protein II (PvDBPII). Given that the disruption of this interaction prevents P. vivax blood-stage infection, a PvDBP-base...

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Publicado en:Malar J
Autores principales: Golassa, Lemu, Messele, Alebachew, Oriero, Eniyou Cheryll, Amambua-Ngwa, Alfred
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8271342/
https://ncbi.nlm.nih.gov/pubmed/34246262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-021-03843-7
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