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Thyroid Hormone Receptor Beta Inhibits PI3K-Akt-mTOR Signaling Axis in Anaplastic Thyroid Cancer via Genomic Mechanisms

Thyroid cancer is the most common endocrine malignancy, and the global incidence has increased rapidly over the past few decades. Anaplastic thyroid cancer (ATC) is highly aggressive, dedifferentiated, and patients have a median survival of fewer than 6 months. Oncogenic alterations in ATC include a...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: Davidson, Cole D, Bolf, Eric L, Gillis, Noelle E, Cozzens, Lauren M, Tomczak, Jennifer A, Carr, Frances E
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8271203/
https://ncbi.nlm.nih.gov/pubmed/34258492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab102
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