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Cerebrospinal fluid monoamine levels in central disorders of hypersomnolence

STUDY OBJECTIVES: Whether the cause of daytime sleepiness in narcolepsy type 1 (NT1) is a direct consequence of the loss of orexin (ORX) neurons or whether low orexin reduces the efficacy of the monoaminergic systems to promote wakefulness is unclear. The neurobiology underlying sleepiness in other...

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Pubblicato in:Sleep
Autori principali: Barateau, Lucie, Jaussent, Isabelle, Roeser, Julien, Ciardiello, Claudio, Kilduff, Thomas S, Dauvilliers, Yves
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8271127/
https://ncbi.nlm.nih.gov/pubmed/33476396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/sleep/zsab012
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