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Dynamic transcriptional and epigenetic changes drive cellular plasticity in the liver

BACKGROUND AND AIMS: Following liver injury, a fraction of hepatocytes adopt features of biliary epithelial cells (BECs) in a process known as biliary reprogramming. The aim of this study was to elucidate the molecular events accompanying this dramatic shift in cellular identity. APPROACH AND RESULT...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Merrell, Allyson J, Peng, Tao, Li, Jinyang, Sun, Kathryn, Li, Bin, Katsuda, Takeshi, Grompe, Markus, Tan, Kai, Stanger, Ben Z.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8271088/
https://ncbi.nlm.nih.gov/pubmed/33423324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.31704
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