A time-resolved experimental–mathematical model for predicting the response of glioma cells to single-dose radiation therapy

PURPOSE: To develop and validate a mechanism-based, mathematical model that characterizes 9L and C6 glioma cells’ temporal response to single-dose radiation therapy in vitro by explicitly incorporating time-dependent biological interactions with radiation. METHODS: We employed time-resolved microsco...

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Detalles Bibliográficos
Publicado en:Integr Biol (Camb)
Main Authors: Liu, Junyan, Hormuth, David A, Davis, Tessa, Yang, Jianchen, McKenna, Matthew T, Jarrett, Angela M, Enderling, Heiko, Brock, Amy, Yankeelov, Thomas E
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2021
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8271006/
https://ncbi.nlm.nih.gov/pubmed/34060613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intbio/zyab010
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