MYC-targeted WDR4 promotes proliferation, metastasis, and sorafenib resistance by inducing CCNB1 translation in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide. However, there still remains a lack of effective diagnostic and therapeutic targets for this disease. Increasing evidence demonstrates that RNA modifications play an important role in the progression of HCC, but the rol...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Xia, Peng, Zhang, Hao, Xu, Kequan, Jiang, Xiang, Gao, Meng, Wang, Ganggang, Liu, Yingyi, Yao, Ye, Chen, Xi, Ma, Weijie, Zhang, Zhonglin, Yuan, Yufeng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8270967/
https://ncbi.nlm.nih.gov/pubmed/34244479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03973-5
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