Complement Plays a Critical Role in Inflammation-Induced Immunoprophylaxis Failure in Mice

Complement impacts innate and adaptive immunity. Using a model in which the human KEL glycoprotein is expressed on murine red blood cells (RBCs), we have shown that polyclonal immunoprophylaxis (KELIg) prevents alloimmunization to transfused RBCs when a recipient is in their baseline state of heath...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Escamilla-Rivera, Vicente, Santhanakrishnan, Manjula, Liu, Jingchun, Gibb, David R., Forsmo, James E., Foxman, Ellen F., Eisenbarth, Stephanie C., Luckey, C. John, Zimring, James C., Hudson, Krystalyn E., Stowell, Sean R., Hendrickson, Jeanne E.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8270673/
https://ncbi.nlm.nih.gov/pubmed/34249009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.704072
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