Biotransformation of Timosaponin BII into Seven Characteristic Metabolites by the Gut Microbiota

Timosaponin BII is one of the most abundant Anemarrhena saponins and is in a phase II clinical trial for the treatment of dementia. However, the pharmacological activity of timosaponin BII does not match its low bioavailability. In this study, we aimed to determine the effects of gut microbiota on t...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Dong, Guo-Ming, Yu, Hang, Pan, Li-Bin, Ma, Shu-Rong, Xu, Hui, Zhang, Zheng-Wei, Han, Pei, Fu, Jie, Yang, Xin-Yu, Keranmu, Adili, Niu, Hai-Tao, Jiang, Jian-Dong, Wang, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8270264/
https://ncbi.nlm.nih.gov/pubmed/34202717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26133861
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