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Characterization of Phase I Hepatic Metabolites of Anti-Premature Ejaculation Drug Dapoxetine by UHPLC-ESI-Q-TOF

Determination of the metabolism pathway of xenobiotics undergoing the hepatic pass is a crucial aspect in drug development since the presence of toxic biotransformation products may result in significant side effects during the therapy. In this study, the complete hepatic metabolism pathway of dapox...

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Publicado en:Molecules
Main Authors: Skibiński, Robert, Trawiński, Jakub, Gawlik, Maciej
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8270242/
https://ncbi.nlm.nih.gov/pubmed/34206424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26133794
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