RASSF1A Suppression as a Potential Regulator of Mechano-Pathobiology Associated with Mammographic Density in BRCA Mutation Carriers

SIMPLE SUMMARY: High mammographic density (MD) is a significant risk factor for the development of breast cancer, as is inheritance of mutations in BRCA1 or BRCA2 tumour suppressor genes. High MD combined with BRCA1/2 gene mutations synergistically increases breast cancer risk, yet BRCA1/2 mutations...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Reye, Gina, Huang, Xuan, Britt, Kara L., Meinert, Christoph, Blick, Tony, Xu, Yannan, Momot, Konstantin I., Lloyd, Thomas, Northey, Jason J., Thompson, Erik W., Hugo, Honor J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8269117/
https://ncbi.nlm.nih.gov/pubmed/34209669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13133251
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