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Mismatch Repair Deficiency as a Predictive and Prognostic Biomarker in Molecularly Classified Endometrial Carcinoma

SIMPLE SUMMARY: We studied mismatch repair (MMR) deficiency as a predictive and prognostic biomarker in endometrial carcinoma. MMR deficiency was associated with poor outcome only when p53 aberrant and polymerase-ϵ mutant tumors were excluded from the MMR proficient subgroup, in accordance with mole...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Loukovaara, Mikko, Pasanen, Annukka, Bützow, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8268938/
https://ncbi.nlm.nih.gov/pubmed/34206702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13133124
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