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Western Diet Decreases the Liver Mitochondrial Oxidative Flux of Succinate: Insight from a Murine NAFLD Model

Mitochondria play an essential role in the pathogenesis of nonalcoholic fatty liver disease (NAFLD). Previously, we found that succinate-activated respiration was the most affected mitochondrial parameter in mice with mild NAFLD. In this study, we focused on the role of succinate dehydrogenase (SDH)...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Staňková, Pavla, Kučera, Otto, Peterová, Eva, Elkalaf, Moustafa, Rychtrmoc, David, Melek, Jan, Podhola, Miroslav, Zubáňová, Veronika, Červinková, Zuzana
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8268937/
https://ncbi.nlm.nih.gov/pubmed/34199098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22136908
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