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Exploiting off-target effects of estrogen deprivation to sensitize estrogen receptor negative breast cancer to immune killing

BACKGROUND: There are highly effective treatment strategies for estrogen receptor (ER)+, progesterone receptor (PR)+, and HER2+ breast cancers; however, there are limited targeted therapeutic strategies for the 10%–15% of women who are diagnosed with triple-negative breast cancer. Here, we hypothesi...

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Pubblicato in:J Immunother Cancer
Autori principali: Wolfson, Benjamin, Padget, Michelle R, Schlom, Jeffrey, Hodge, James W
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Publishing Group 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8268928/
https://ncbi.nlm.nih.gov/pubmed/34244306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-002258
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