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A pH-Sensitive Polymeric Micellar System Based on Chitosan Derivative for Efficient Delivery of Paclitaxel

In this study, an amphiphilic conjugate based on mPEG and cholesterol-modified chitosan with hydrazone bonds in the molecules (mPEG-CS-Hz-CH) was successfully synthesized. Using the polymer as the carrier, the paclitaxel (PTX)-loaded mPEG-CS-Hz-CH micelles were prepared by an ultrasonic probe method...

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Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Han, Yang, Pan, Jieyi, Liang, Na, Gong, Xianfeng, Sun, Shaoping
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8268857/
https://ncbi.nlm.nih.gov/pubmed/34206347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22136659
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