High Density of NRF2 Expression in Malignant Cells Is Associated with Increased Risk of CNS Metastasis in Early-Stage NSCLC

SIMPLE SUMMARY: We retrospectively analyzed 304 patients with surgically removed non-small cell lung cancer (NSCLC). Multiplex antibody staining of nuclear factor erythroid 2-related factor 2 (NRF2) and thioredoxin reductase 1 (TrxR1) was conducted and scored in cytokeratin-positive (CK+) cells with...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Tsakonas, Georgios, Martín-Bernabé, Alfonso, Rounis, Konstantinos, Moreno-Ruiz, Pablo, Botling, Johan, De Petris, Luigi, Ylipää, Antti, Mezheyeuski, Artur, Micke, Patrick, Östman, Arne, Ekman, Simon
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8268817/
https://ncbi.nlm.nih.gov/pubmed/34202448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13133151
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