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Lomeguatrib Increases the Radiosensitivity of MGMT Unmethylated Human Glioblastoma Multiforme Cell Lines

Background: Treatment resistance of glioblastoma multiforme to chemo- and radiotherapy remains a challenge yet to overcome. In particular, the O(6)-methylguanine-DNA-methyltransferase (MGMT) promoter unmethylated patients have only little benefit from chemotherapy treatment using temozolomide since...

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Pubblicato in:Int J Mol Sci
Autori principali: Kirstein, Anna, Schilling, Daniela, Combs, Stephanie E., Schmid, Thomas E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8268804/
https://ncbi.nlm.nih.gov/pubmed/34202589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22136781
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