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PRP4 Promotes Skin Cancer by Inhibiting Production of Melanin, Blocking Influx of Extracellular Calcium, and Remodeling Cell Actin Cytoskeleton

Pre-mRNA processing factor 4B (PRP4) has previously been shown to induce epithelial-mesenchymal transition (EMT) and drug resistance in cancer cell lines. As melanin plays an important photoprotective role in the risk of sun-induced skin cancers, we have investigated whether PRP4 can induce drug res...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Ahmed, Muhammad Bilal, Islam, Salman Ul, Lee, Young Sup
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8268783/
https://ncbi.nlm.nih.gov/pubmed/34209674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22136992
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