Natural Merosesquiterpenes Activate the DNA Damage Response via DNA Strand Break Formation and Trigger Apoptotic Cell Death in p53-Wild-Type and Mutant Colorectal Cancer

SIMPLE SUMMARY: Bowel cancer is a serious disease, which affects many people worldwide. Unfortunately, the disease is often diagnosed in an advanced stage, which impairs the chance of survival. Furthermore, resistance to therapy occurs frequently. Thus, novel therapeutic approaches are required to i...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Jiso, Apisada, Demuth, Philipp, Bachowsky, Madeleine, Haas, Manuel, Seiwert, Nina, Heylmann, Daniel, Rasenberger, Birgit, Christmann, Markus, Dietrich, Lea, Brunner, Thomas, Riyanti, Schäberle, Till F., Plubrukarn, Anuchit, Fahrer, Jörg
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8268692/
https://ncbi.nlm.nih.gov/pubmed/34209047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13133282
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