The Footprint of Kynurenine Pathway in Neurodegeneration: Janus-Faced Role in Parkinson’s Disorder and Therapeutic Implications

Progressive degeneration of neurons and aggravation of dopaminergic neurons in the substantia nigra pars compacta results in the loss of dopamine in the brain of Parkinson’s disease (PD) patients. Numerous therapies, exhibiting transient efficacy have been developed; however, they are mostly accompa...

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發表在:Int J Mol Sci
Main Authors: Behl, Tapan, Kaur, Ishnoor, Sehgal, Aayush, Singh, Sukhbir, Bhatia, Saurabh, Al-Harrasi, Ahmed, Zengin, Gokhan, Bumbu, Adrian Gheorghe, Andronie-Cioara, Felicia Liana, Nechifor, Aurelia Cristina, Gitea, Daniela, Bungau, Alexa Florina, Toma, Mirela Marioara, Bungau, Simona Gabriela
格式: Artigo
語言:Inglês
出版: MDPI 2021
主題:
Review
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8268239/
https://ncbi.nlm.nih.gov/pubmed/34201647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22136737
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